Medisco MesO PDRN Ampoule packaging and the vials displayed on a white background
Close-up of a single Medisco MesO PDRN Ampoule vial featuring sodium hyaluronate and PDRN.
Medisco MesO PDRN Ampoule vials and box arranged on an orange background.
Medisco MesO PDRN Ampoule box and vials displayed with UK and EU certification icons.
Medisco MesO PDRN Ampoule packaging boxes displayed on a bright orange background.
Front view of the Medisco MesO PDRN Ampoule packaging box on a clean white background.
Medisco MesO PDRN Ampoule vials showcased on white blocks against an orange backdrop.
Medisco MesO PDRN key ingredients benefits
Medisco MesO PDRN Advanced Skin Regeneration Ampoule box with orange inner box
Medisco MesO PDRN Advanced Skin Regeneration Ampoule open kit with five vials
Medisco MesO PDRN Advanced Skin Regeneration Ampoule vials open box with orange packaging
Medisco MesO PDRN Advanced Skin Regeneration Ampoule 3ml vial with sodium DNA and hyaluronate
Medisco MesO PDRN Ampoule packaging and the vials displayed on a white background
Close-up of a single Medisco MesO PDRN Ampoule vial featuring sodium hyaluronate and PDRN.
Medisco MesO PDRN Ampoule vials and box arranged on an orange background.
Medisco MesO PDRN Ampoule box and vials displayed with UK and EU certification icons.
Medisco MesO PDRN Ampoule packaging boxes displayed on a bright orange background.
Front view of the Medisco MesO PDRN Ampoule packaging box on a clean white background.
Medisco MesO PDRN Ampoule vials showcased on white blocks against an orange backdrop.
Medisco MesO PDRN key ingredients benefits
Medisco MesO PDRN Advanced Skin Regeneration Ampoule box with orange inner box
Medisco MesO PDRN Advanced Skin Regeneration Ampoule open kit with five vials
Medisco MesO PDRN Advanced Skin Regeneration Ampoule vials open box with orange packaging
Medisco MesO PDRN Advanced Skin Regeneration Ampoule 3ml vial with sodium DNA and hyaluronate

Medisco MesO PDRN – Advanced Skin Regeneration Ampoule

SKU: DP-STAYVE-MESOPDRN-K

Medisco MesO PDRN – Advanced Skin Regeneration Ampoule

SKU: DP-STAYVE-MESOPDRN-K
Selection
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Good for:
Anti-Ageing Dehydrated Skin Fine Lines & Wrinkles Hyperpigmentation Scarring Sun Damage Toning & Firming
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The next-generation microneedling pen, designed for an easier at-home routine.

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Limited-time launch offer. Ends 31 October 2026.

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*T&Cs: Offer valid at us.drpen.co until 31 October 2026 at 11:59 PM PDT. No code required. Offer applies to the Dr. Pen M8 Max microneedling pen only and excludes all other products, including M8 Max cartridges. Prices as marked. No rainchecks. While stocks last. Dr. Pen Global reserves the right to amend or withdraw this offer at any time.
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Advanced PDRN Skin Regeneration for Enhanced Microneedling Results 

Medisco MesO PDRN is a professional-grade skin regeneration ampoule designed to maximize microneedling results and support visible skin recovery. Powered by high-purity Sodium DNA (PDRN), this advanced formula helps promote skin renewal, improve elasticity, and strengthen the skin’s natural barrier for a healthier, more resilient complexion.

Developed for use with microneedling devices, the lightweight ampoule helps deliver active ingredients more effectively into the skin, supporting smoother texture, enhanced hydration, and a more radiant appearance. Enriched with Sodium Hyaluronate and other skin-conditioning actives, Medisco MesO PDRN helps replenish moisture, improve skin tone, and support a revitalized, youthful-looking complexion throughout the recovery process.
Medisco MesO PDRN is built around a focused, regeneration-first formula designed to maximise microneedling outcomes and support visible skin recovery.

Core Regenerative Complex

  • Sodium DNA (PDRN): A clinically recognised regenerative active that supports cellular repair and renewal. Helps stimulate collagen production, strengthen dermal structure, and improve overall skin resilience over time.
  • Sodium Hyaluronate: Delivers deep, long-lasting hydration to support post-treatment recovery. Helps smooth the appearance of fine lines while improving skin softness and flexibility.

Targeted Ageing + Brightening Support

  • Adenosine: Supports skin elasticity and firmness by encouraging collagen and elastin activity. Helps soften the look of wrinkles and improve skin texture.
  • Niacinamide (Vitamin B3): Visibly refines skin tone and clarity by helping regulate excess melanin transfer. Supports brighter, more even-looking skin with continued use.
  • Glutathione: A powerful antioxidant that helps defend against environmental stressors while supporting skin brightness and overall radiance.
  • Accelerated skin renewal: Supports rapid cellular repair to help restore compromised, tired, or damaged skin.
  • Stronger skin barrier: Reinforces the skin’s natural defences for improved resilience and long-term skin health.
  • Visible line and wrinkle reduction: Encourages collagen production to smooth fine lines and refine skin texture.
  • Improved firmness and elasticity: Supports elastin structure for skin that looks firmer, more lifted, and resilient.
  • Brighter, more even tone: Helps minimise the appearance of pigmentation and promotes a clearer, more luminous complexion.
  • Deep, sustained hydration: Delivers lasting moisture to maintain plumpness and comfort throughout the skin cycle.
  • 5 x 3ml vials (15ml total)
  • Also available as a single 3ml ampoule

Full Ingredient List

Water, Sodium Hyaluronate, Sodium DNA, Glucose, Sodium Phosphate, Disodium Phosphate, Sodium Bicarbonate, Calcium Chloride, Potassium Chloride, Magnesium Sulfate, Glycine, Proline, Hydroxyproline, Lysine HCl, Threonine, Glutamic Acid, Arginine, Aspartic Acid, Serine, Valine, Histidine, Methionine, Taurine, Alanine, Phenylalanine, Acetyl Cysteine, Tyrosine, Glutathione, Niacinamide, Adenosine, Inositol, Thiamine HCl, Pyridoxine HCl, Calcium Pantothenate, sh-Oligopeptide-5, sh-Octapeptide-4, sh-Decapeptide-7, Nicotinoyl Tripeptide-1, Caffeoyl sh-Decapeptide-9

Expiry

Shelf-life: 24 months from production.

Storage

  • Store in a cool, dry place at 2–28°C.
  • Avoid direct sunlight.
  • Use immediately after opening. Do not store leftover product.
Area of Application: Face. Designed for microneedling users seeking enhanced absorption and visible brightening results.

Step-by-Step Instructions (Microneedling Use)

  1. Cleanse thoroughly: Ensure the skin is completely cleansed and sanitised prior to treatment.
  2. Prepare your device: Select an appropriate needle depth based on experience level and treatment goals.
  3. Apply the ampoule: Evenly distribute Medisco MesO PDRN across the treatment area.
  4. Microneedle: Perform the procedure using a microneedling pen. For best practice, begin at the jawline and work upward toward the forehead, moving opposite to facial muscle direction.

The recommended frequency is once every 3 to 4 days, but it may vary depending on the length of the treatment needle:

  • 0.25 mm needles: Every 3–4 days
  • 0.50 mm needles: Every 1–2 weeks
  • 1.00 mm needles: Every 3–4 weeks

Important Usage Notes

  • Do not combine multiple Medisco MesO ampoules in a single session.
  • Allow 1–2 weeks between different MesO serums.
  • Always follow strict hygiene protocols and appropriate post-treatment care.
  • Single-use only. Any remaining solution must not be stored or reused after opening.

Disclaimer
This is a professional-grade microneedling ampoule. Suitable for experienced home users who understand microneedling techniques, sterilisation, and aftercare. Consult a qualified skincare professional if unsure. Not intended to diagnose, treat, cure, or prevent medical conditions.

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Microneedling, big results

Microneedling users have seen:

90%

Visible improvements in fine lines and wrinkles.
(after 3-6 treatments spaced about 4-6 weeks apart.)

70%

Reduction in pigmentation.
(over a few months of consistent treatment)

70%

Improvement across acne scars, surgical scars, and stretch marks.

80-85%

Increase in collagen production, resulting in better skin elasticity.
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